Independent emergence of a vaccine-induced escape mutant of hepatitis B virus.

doi:10.1016/0168-8278(91)90037-c

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Article

Independent emergence of a vaccine-induced escape mutant of hepatitis B virus.

Journal of hepatology - 1 Jan 1991

Harrison T J, Hopes E A, Oon C J, Zanetti A R, Zuckerman A J

Abstract excerpt

We investigated the case of a child who was vaccinated at birth against hepatitis B and was also given hepatitis B immune globulin, but who nevertheless later became infected with the virus. Hepatitis B virus-specific deoxyribonucleic acid covering the region of the genome encoding the predominant a epitope of hepatitis B surface antigen was amplified using the polymerase chain reaction and the nucleotide...

Topics

Amino Acid Sequence
Base Sequence
DNA
Epitopes
Genome, Viral
Hepatitis B
Hepatitis B Surface Antigens
Hepatitis B Vaccines
Hepatitis B virus
Humans
Infant, Newborn
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Oligodeoxyribonucleotides

Polymerase Chain Reaction

Time Factors

Vaccines, Synthetic

Viral Hepatitis Vaccines

Source

Open in PubMed

Identifiers

PMID: 1726588
DOI: 10.1016/0168-8278(91)90037-c

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1726588-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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