Article
Independent emergence of a vaccine-induced escape mutant of hepatitis B virus.
Journal of hepatology - 1 Jan 1991
Harrison T J, Hopes E A, Oon C J, Zanetti A R, Zuckerman A J
Abstract excerpt
We investigated the case of a child who was vaccinated at birth against hepatitis B and was also given hepatitis B immune globulin, but who nevertheless later became infected with the virus. Hepatitis B virus-specific deoxyribonucleic acid covering the region of the genome encoding the predominant a epitope of hepatitis B surface antigen was amplified using the polymerase chain reaction and the nucleotide...
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