Article
The ADRB3 Trp64Arg variant and obesity in African-American breast cancer cases.
International journal of obesity (2005) - 1 Jul 2007
McKean-Cowdin R, Li X, Bernstein L, McTiernan A, Ballard-Barbash R, Gauderman W J, Gilliland F
Abstract excerpt
OBJECTIVE: To determine if a missense change at codon 64 of ADRB3 (Trp64Arg), a candidate obesity gene, is associated with obesity and levels of subcutaneous or visceral fat in African-American breast cancer cases. Several observational studies have found that women, who are overweight or obese at the time of diagnosis, as well as those who gain weight after diagnosis, are at greater risk for breast cancer...
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