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Article

HIV-1 Infection Increases the Expression of Human Endogenous Retroviruses Type K (HERV-K) <i>in Vitro</i>

1 Jan 2007

Abstract excerpt

Antibodies to HERV-K antigens have been linked to HIV-1 infection and expression of HERV-K proteins generates T-cell cytotoxic responses in many cancers. HERV-K RNA and protein abundance was measured in HIV-1-infected and control cells. In vitro exposure of HIV-1 laboratory-adapted and primary isolates on U87MG cells increased the expression of HERV-K RNA in a dose-dependent manner. HERV-K RNA and protein burdens...

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Identifiers

PMID: 17263641
DOI: 10.1089/aid.2006.0117

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