Article
Secretion of an epidermal growth factor-like growth factor by epidermal growth factor-independent rat mammary carcinoma cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Nov 1991
Ethier S P, Moorthy R, Dilts C A
Abstract excerpt
Rat mammary carcinoma (RMC) cells derived from serially transplantable mammary tumors are independent of epidermal growth factor (EGF) for long-term growth in serum-free medium. This phenotype is in contrast to that of normal mammary epithelial cells or cells derived from nontransplantable tumors...
Topics
- Animals
- Carcinoma
- Culture Media
- Epidermal Growth Factor
- ErbB Receptors
- Female
- Growth Substances
- Mammary Neoplasms, Experimental
- Neoplasm Proteins
- Phenotype
- Phosphoproteins
- Phosphotyrosine
- Rats
- Tyrosine