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Article

High-resolution genomic arrays facilitate detection of novel cryptic chromosomal lesions in myelodysplastic syndromes.

Experimental hematology - 1 Feb 2007

O'Keefe Christine L, Tiu Ramon, Gondek Lukasz P, Powers Jennifer, Theil Karl S, Kalaycio Matt, Lichtin Alan, Sekeres Mikkael A, Maciejewski Jaroslaw P

Abstract excerpt

OBJECTIVE: Unbalanced chromosomal aberrations are common in myelodysplastic syndromes and have prognostic implications. An increased frequency of cytogenetic changes may reflect an inherent chromosomal instability due to failure of DNA repair. Therefore, it is likely that chromosomal defects in myelodysplastic syndromes may be more frequent than predicted by metaphase cytogenetics and new cryptic lesions may be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17258073
DOI: 10.1016/j.exphem.2006.09.016
PMCID: PMC2613764

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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