Article
Identification of novel therapeutic targets for HIV infection through functional genomic cDNA screening.
Virology - 25 May 2007
Nguyen Deborah G, Yin Hong, Zhou Yingyao, Wolff Karen C, Kuhen Kelli L, Caldwell Jeremy S
Abstract excerpt
Despite decades of research, HIV remains a global health threat. Issues of multi-drug resistance and lack of an effective vaccine have recently led to the targeting of host factors for anti-viral drug development. While a few genome-wide screens for novel HIV co-factors have been reported, the promise of finding a therapeutic target has yet to be realized. Here, we report a screen of a cDNA library representing...
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