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Article

Artificial regulation of <i>ospC</i> expression in <i>Borrelia burgdorferi</i>

8 Jan 2007

Abstract excerpt

Outer surface lipoprotein (Osp) C is a virulence factor required for transmission of the Lyme disease agent, Borrelia burgdorferi. We have constructed an inducible promoter system to study the function and regulation of OspC by integrating regulatory elements from the Escherichia coli lac operon into the B. burgdorferi genome. An inducible promoter (flacp) was constructed by inserting a synthetic lac operator...

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PMID: 17257307
DOI: 10.1111/j.1365-2958.2007.05593.x

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Artificial regulation of <i>ospC</i> expression in <i>Borrelia burgdorferi</i>PMID 17257307Read ↗

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