Article
No association of an SDHC gene polymorphism with gastric cancer.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2000
Goto Yasuyuki, Ando Takafumi, Naito Mariko, Goto Hidemi, Hamajima Nobuyuki
Abstract excerpt
It is widely reported that reactive oxygen species (ROS) cause apotosis and carcinogenesis. Marked infiltration of activated leukocyte and enhanced production of ROS appear to occur in the gastric mucosa infected with Helicobacter pylori (H. pylori). The previous studies reported that the mutation of the succinate dehydrogenase subunit C (SDHC) gene caused the increase in superoxide anion (O(2)(-)) and oxidative...
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