Article
Molecular biology of otosclerosis.
Advances in oto-rhino-laryngology - 1 Jan 2007
McKenna Michael J, Kristiansen Arthur G
Abstract excerpt
Otosclerosis is a bone disease of the human otic capsule, which is among the most common causes of acquired hearing loss. The pathologic process is characterized by a wave of abnormal bone remodeling in specific sites of predilection within the endochondral layer of the temporal bone. Although the cause of otosclerosis remains uncertain, there is a clear genetic predisposition with half of all cases occurring in...
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