Article
Suppression of hyphal formation and virulence of Candida albicans by natural and synthetic compounds
3 Jul 2021
Abstract excerpt
Candida albicans undergoes a morphological yeast-to-hyphal transition during infection, which plays a significant role in its pathogenesis. The filamentous morphology of the hyphal form has been identified as a virulence factor as it facilitates surface adherence, intertwining with biofilm, invasion, and damage to host tissues and organs. Hence, inhibition of filamentation in addition to biofilm formation is...
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