Article
Application of quantum dots to multicolor microarray experiments: four-color genotyping.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2007
Karlin-Neumann George, Sedova Marina, Falkowski Mat, Wang Zhiyong, Lin Steven, Jain Maneesh
Abstract excerpt
Highly multiplexed genomics assays are challenged by the need for a sufficient signal-to-noise ratio for each marker scored on a microarray-detection platform. Typically, as the number of markers scored (or target complexity) increases, either more assay-target material must be applied to the array or the specific activity of each marker must be proportionately increased. However, hybridization of excessive...
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