Article
Lipolysis is altered in MHC class I zinc-alpha(2)-glycoprotein deficient mice.
FEBS letters - 6 Feb 2007
Rolli Véronique, Radosavljevic Mirjana, Astier Valérie, Macquin Cécile, Castan-Laurell Isabelle, Visentin Virgile, Guigné Charlotte, Carpéné Christian, Valet Philippe, Gilfillan Susan, Bahram Seiamak
Abstract excerpt
Non-conventional major histocompatibility complex class I molecules are involved in a variety of physiological functions, most at the periphery of the immune system per se. Zinc-alpha(2)-glycoprotein (ZAG), the sole soluble member of this superfamily has been implicated in cachexia, a poorly understood yet life-threatening, severe wasting syndrome. To further ascertain the role of ZAG in lipid metabolism and...
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