Article
Conserved alternative and antisense transcripts at the programmed cell death 2 locus.
BMC genomics - 18 Jan 2007
Mihola Ondrej, Forejt Jiri, Trachtulec Zdenek
Abstract excerpt
BACKGROUND: The programmed cell death 2 (Pdcd2) gene on mouse chromosome 17 was evaluated as a member of a highly conserved synteny, a candidate for an imprinted locus, and a candidate for the Hybrid sterility 1 (Hst1) gene. RESULTS: New mouse transcripts were identified at this locus: an alternative Pdcd2 mRNA skipping the last two coding exons and two classes of antisense RNAs. One class of the antisense RNA...
Topics
- Alleles
- Alternative Splicing
- Animals
- Apoptosis
- Apoptosis Regulatory Proteins
- Chickens
- Chromosome Mapping
- Expressed Sequence Tags
- Genomic Imprinting
- Humans
- Male
- Mice
- Molecular Sequence Data
- Polymerase Chain Reaction
- RNA, Messenger
- Rats
