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Article

Replicative homeostasis: a fundamental mechanism mediating selective viral replication and escape mutation.

Virology journal - 11 Feb 2005

Sallie Richard

Abstract excerpt

Hepatitis C (HCV), hepatitis B (HBV), the human immunodeficiency viruses (HIV), and other viruses that replicate via RNA intermediaries, cause an enormous burden of disease and premature death worldwide. These viruses circulate within infected hosts as vast populations of closely related, but genetically diverse, molecules known as "quasispecies". The mechanism(s) by which this extreme genetic and antigenic...

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Identifiers

PMID: 15707489
DOI: 10.1186/1743-422X-2-10
PMCID: PMC552327

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Source receipt: pubmed, retrieved 7 Sept 2026.

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