Article
Varying responses of human cells with discrepant p53 activity to ionizing radiation and heat shock exposure.
Cell proliferation - 1 Feb 2007
Tokalov S V, Pieck S, Gutzeit H O
Abstract excerpt
OBJECTIVES: Both heat shock (HS) and ionizing radiation have an impact on the cell cycle and may induce cell cycle arrest or apoptosis. Mutations of the p53 gene are observed at a high frequency in human tumours and are recognized in about half of all human cancers. Sensitivity to radiation, heat...
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