Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MT1-MMP as a Key Regulator of Metastasis

31 Aug 2023

Abstract excerpt

Membrane type1-matrix metalloproteinase (MT1-MMP) is a member of metalloproteinases that is tethered to the transmembrane. Its major function in cancer progression is to directly degrade the extracellular matrix components, which are mainly type I-III collagen or indirectly type IV collagen through the activation of MMP-2 with a cooperative function of the tissue inhibitor of metalloproteinase-2 (TIMP-2). MT1-MMP...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Peptidase Inhibition and Analysis
Share to Protease and Inhibitor Mechanisms
Share to Signaling Pathways in Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37681919
DOI: 10.3390/cells12172187

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MT1-MMP as a Key Regulator of MetastasisPMID 37681919Read ↗

Insights Into the Role of Matrix Metalloproteinases in Cancer and its Various Therapeutic Aspects: A ReviewSemantic proximity Read ↗

Novel Roles of MT1-MMP and MMP-2: Beyond the Extracellular MilieuSemantic proximity Read ↗

Matrix Metalloproteinases in Chemoresistance: Regulatory Roles, Molecular Interactions, and Potential InhibitorsSemantic proximity Read ↗

MT4-MMP: The GPI-Anchored Membrane-Type Matrix Metalloprotease with Multiple Functions in DiseasesSemantic proximity Read ↗

MT-MMPs play pivotal roles in cancer dissemination.Semantic proximity Read ↗

Matrix Metalloproteinase-2 (MMP-2): As an Essential Factor in Cancer ProgressionSemantic proximity Read ↗

Analysis of the expression and prognostic value of MT1-MMP, β1-integrin and YAP1 in gliomaSemantic proximity Read ↗

Matrix metalloproteinases at a glanceSemantic proximity Read ↗

Matrix Metalloproteinases and Their Role in Oncogenesis: A ReviewSemantic proximity Read ↗

Cellular and Molecular Mechanisms of MT1-MMP-Dependent Cancer Cell InvasionSemantic proximity Read ↗

Roles of matrix metalloproteinases in cancer progression and their pharmacological targetingSemantic proximity Read ↗

Matrix metalloproteinases in cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.