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Activation of dendritic cells by the Gal‐lectin of <i>Entamoeba histolytica</i> drives Th1 responses <i>in vitro</i> and <i>in vivo</i>

11 Jan 2007

Abstract excerpt

Amebiasis is a human disease caused by the protozoan intestinal parasite Entamoeba histolytica. Vaccine development has focused on the parasite's surface galactose-N-acetyl-D-galactosamine inhibitable lectin (Gal-lectin) as a protective antigen. The Gal-lectin is immunogenic and has been shown to induce Th1 cytokines in vitro and in vivo. The immunological basis of the protective immune response elicited by the...

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PMID: 17219364
DOI: 10.1002/eji.200636476

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