Article
Epidermolysis bullosa: hereditary skin fragility diseases as paradigms in cell biology.
Archives of dermatological research - 1 Jan 1994
Eady R A, Dunnill M G
Abstract excerpt
Recent research into the molecular basis of epidermolysis bullosa has provided a unique insight into a variety of mechanisms in normal cell biology, such as cell-matrix interactions, and has uncovered an excellent model for studies on keratin intermediate filaments. The simplex forms of epidermolysis bullosa are caused by mutations in the genes for the basal epidermal keratins, K5 and K14. Most mutations affect...
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