Article
The cDNA 385C to A missense polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) is associated with overweight/obesity but not with binge eating disorder in overweight/obese women.
Psychoneuroendocrinology - 1 May 2008
Monteleone Palmiero, Tortorella Alfonso, Martiadis Vassilis, Di Filippo Carmela, Canestrelli Benedetta, Maj Mario
Abstract excerpt
Endocannabinoids are involved in the modulation of eating behavior; hence, alterations of this system may play a role in obesity. Recently, a single nucleotide polymorphism (cDNA 385C to A) of the gene coding for fatty acid amide hydrolase (FAAH), the major degrading enzyme of endocannabinoids, has been found to be associated with obesity. However, the possibility that the FAAH gene cDNA 385C to A single...
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