Article
A big-data approach to understanding metabolic rate and response to obesity in laboratory mice.
eLife - 1 May 2020
Corrigan June K, Ramachandran Deepti, He Yuchen, Palmer Colin J, Jurczak Michael J, Chen Rui, Li Bingshan, Friedline Randall H, Kim Jason K, Ramsey Jon J, Lantier Louise, McGuinness Owen P, Banks Alexander S
Abstract excerpt
Maintaining a healthy body weight requires an exquisite balance between energy intake and energy expenditure. To understand the genetic and environmental factors that contribute to the regulation of body weight, an important first step is to establish the normal range of metabolic values and primary sources contributing to variability. Energy metabolism is measured by powerful and sensitive indirect calorimetry...
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