Article
Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.
Behavioural brain research - 15 Oct 2018
Fuchs Helmut, Aguilar-Pimentel Juan Antonio, Amarie Oana V, Becker Lore, Calzada-Wack Julia, Cho Yi-Li, Garrett Lillian, Hölter Sabine M, Irmler Martin, Kistler Martin, Kraiger Markus, Mayer-Kuckuk Philipp, Moreth Kristin, Rathkolb Birgit, Rozman Jan, da Silva Buttkus Patricia, Treise Irina, Zimprich Annemarie, Gampe Kristine, Hutterer Christine, Stöger Claudia, Leuchtenberger Stefanie, Maier Holger, Miller Manuel, Scheideler Angelika, Wu Moya, Beckers Johannes, Bekeredjian Raffi, Brielmeier Markus, Busch Dirk H, Klingenspor Martin, Klopstock Thomas, Ollert Markus, Schmidt-Weber Carsten, Stöger Tobias, Wolf Eckhard, Wurst Wolfgang, Yildirim Ali Önder, Zimmer Andreas, Gailus-Durner Valérie, Hrabě de Angelis Martin
Abstract excerpt
Since decades, model organisms have provided an important approach for understanding the mechanistic basis of human diseases. The German Mouse Clinic (GMC) was the first phenotyping facility that established a collaboration-based platform for phenotype characterization of mouse lines. In order to address individual projects by a tailor-made phenotyping strategy, the GMC advanced in developing a series of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.