Article
A functional SNP of interferon-gamma gene is important for interferon-alpha-induced and spontaneous recovery from hepatitis C virus infection.
Proceedings of the National Academy of Sciences of the United States of America - 16 Jan 2007
Huang Ying, Yang Huiying, Borg Brian B, Su Xiaowen, Rhodes Shannon L, Yang Kai, Tong Xiaomei, Tang George, Howell Charles D, Rosen Hugo R, Thio Chloe L, Thomas David L, Alter Harvey J, Sapp Ronda K, Liang T Jake
Abstract excerpt
Cytokine polymorphisms are associated with disease outcome and interferon (IFN) treatment response in hepatitis C virus (HCV) infection. We genotyped eight SNPs spanning the entire IFN-gamma gene in two cohorts and assessed the association between those polymorphisms and treatment response or spo...
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