Article
Escherichia coli tatC mutations that suppress defective twin-arginine transporter signal peptides.
Journal of molecular biology - 23 Nov 2007
Strauch Eva-Maria, Georgiou George
Abstract excerpt
In vitro studies have suggested that the TatBC complex serves as the receptor for signal peptides targeted for export via the twin-arginine translocation (Tat) pathway. Substitution of the hallmark twin-arginine dipeptide with two lysines abrogates export of physiological substrates in all organisms. We report the isolation and characterization of suppressor mutations that allow export of an ssTor(KK)-GFP-SsrA...
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