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Article

Retinoids restore normal cyclic nucleotide sensitivity of mutant ion channels associated with cone dystrophy.

Molecular vision - 29 Dec 2006

Tetreault Michelle L, Horrigan Diana M, Kim Jennifer A, Zimmerman Anita L

Abstract excerpt

PURPOSE: To determine whether inhibition of cyclic nucleotide-gated (CNG) ion channels by retinoids might be useful in treating degenerative retinal diseases in which either the CNG channels are hypersensitive to 3',5'-cyclic guanosine monophosphate (cGMP) or the photoreceptor cGMP concentration...

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PMID: 17213799

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17213799-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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