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Article

DNA repair gene polymorphisms and genetic predisposition to cutaneous melanoma.

Carcinogenesis - 1 May 2007

Povey Joanne E, Darakhshan Fatemeh, Robertson Karen, Bisset Yvonne, Mekky Magda, Rees Jonathan, Doherty Val, Kavanagh Gina, Anderson Niall, Campbell Harry, MacKie Rona M, Melton David W

Abstract excerpt

The incidence of cutaneous melanoma is rising rapidly in a number of countries. The key environmental risk factor is exposure to the ultraviolet (UV) component in sunlight. The nucleotide excision repair (NER) pathway deals with the main forms of UV-induced DNA damage. We have investigated the hypothesis that polymorphisms in NER genes constitute genetic susceptibility factors for melanoma. However, not all...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17210993
DOI: 10.1093/carcin/bgl257

Genes

ERCC1
VDR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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