Article
Ductal carcinoma in situ in BRCA mutation carriers.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Feb 2007
Hwang E Shelley, McLennan Jane L, Moore Dan H, Crawford Beth B, Esserman Laura J, Ziegler John L
Abstract excerpt
PURPOSE: The current literature suggests that ductal carcinoma in situ (DCIS) of the breast is infrequently diagnosed in patients with BRCA germline mutations. We studied women at high risk of hereditary breast cancer syndromes who underwent testing for BRCA1 and BRCA2 to estimate DCIS prevalence and incidence in known BRCA-positive women compared with high-risk women who were mutation negative. METHODS: We...
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