Article
Predictive factors for BRCA1/BRCA2 mutations in women with ductal carcinoma in situ.
Cancer - 15 Mar 2012
Bayraktar Soley, Elsayegh Nisreen, Gutierrez Barrera Angelica M, Lin Heather, Kuerer Henry, Tasbas Tunc, Muse Kimberly I, Ready Kaylene, Litton Jennifer, Meric-Bernstam Funda, Hortobagyi Gabriel N, Albarracin Constance T, Arun Banu
Abstract excerpt
BACKGROUND: It is unclear whether women with ductal carcinoma in situ (DCIS), like their counterparts with invasive breast cancer, warrant genetic risk assessment and testing on the basis of high-risk variables. The authors of this report identified predictive factors for mutations in the breast cancer-susceptibility genes BRCA1 and BRCA2 in women who were diagnosed with DCIS. METHODS: One hundred eighteen women...
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