Article
BRCA mutations in women with ductal carcinoma in situ.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jul 2007
Smith Karen Lisa, Adank Muriel, Kauff Noah, Lafaro Kelly, Boyd Jeff, Lee Johanna B, Hudis Clifford, Offit Kenneth, Robson Mark
Abstract excerpt
PURPOSE: The strength of the association between ductal carcinoma in situ (DCIS) and BRCA mutations has not been defined. EXPERIMENTAL DESIGN: Mutation frequency was compared in three groups: (1) a prevalent series of women with DCIS, (2) an incident series of women with DCIS, and (3) a clinic-based series of women with DCIS referred for hereditary cancer risk assessment. In groups 1 and 2, limited to Ashkenazi...
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