Article
Genomewide scan in Ashkenazi Jewish families demonstrates evidence of linkage of ocular refraction to a QTL on chromosome 1p36.
Human genetics - 1 May 2006
Wojciechowski Robert, Moy Chris, Ciner Elise, Ibay Grace, Reider Lauren, Bailey-Wilson Joan E, Stambolian Dwight
Abstract excerpt
UNLABELLED: The development of refractive error is mediated by both environmental and genetic factors. We performed regression-based quantitative trait locus (QTL) linkage analysis on Ashkenazi Jewish families to identify regions in the genome responsible for ocular refraction. We measured refractive error on individuals in 49 multi-generational American families of Ashkenazi Jewish descent. The average family...
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