Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neutrophilia in LFA-1-deficient mice confers resistance to listeriosis: possible contribution of granulocyte-colony-stimulating factor and IL-17.

Journal of immunology (Baltimore, Md. : 1950) - 15 May 2003

Miyamoto Mamiko, Emoto Masashi, Emoto Yoshiko, Brinkmann Volker, Yoshizawa Izumi, Seiler Peter, Aichele Peter, Kita Eiji, Kaufmann Stefan H E

Abstract excerpt

LFA-1 (CD11a/CD18) plays a crucial role in various inflammatory responses. In this study, we show that LFA-1(-/-) mice are far more resistant to Listeria monocytogenes infection than LFA-1(+/-) mice. Consistent with this, we found the following: 1) the numbers of granulocytes infiltrating the liver were markedly higher in LFA-1(-/-) mice than in LFA-1(+/-) mice, 2) increased antilisterial resistance in LFA-1(-/-)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Granulocyte Colony-Stimulating Factor
Share to Granulocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunosuppression Therapy

Share to Leukocytosis

Share to Listeria

Share to Listeriosis

Share to Lymphocyte Function-Associated Antigen-1

Share to Neutrophil Infiltration

Source

Identifiers

PMID: 12734371
DOI: 10.4049/jimmunol.170.10.5228

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neutrophilia in LFA-1-deficient mice confers resistance to listeriosis: possible contribution of granulocyte-colony-stimulating factor and IL-17.PMID 12734371Read ↗

Aberrant macrophage and neutrophil population dynamics and impaired Th1 response to Listeria monocytogenes in colony-stimulating factor 1-deficient mice.Semantic proximity Read ↗

Inflammasome and Fas-Mediated IL-1β Contributes to Th17/Th1 Cell Induction in Pathogenic Bacterial Infection In VivoSemantic proximity Read ↗

Lymphocytes are detrimental during the early innate immune response against Listeria monocytogenes.Semantic proximity Read ↗

CD1d-independent regulation of NKT cell migration and cytokine production upon Listeria monocytogenes infection.Semantic proximity Read ↗

G-CSF preferentially supports the generation of gut-homing Gr-1high macrophages in M-CSF-treated bone marrow cells.Semantic proximity Read ↗

Caspase-1 regulates Escherichia coli sepsis and splenic B cell apoptosis independently of interleukin-1beta and interleukin-18.Semantic proximity Read ↗

Different roles of alpha beta and gamma delta T cells in immunity against an intracellular bacterial pathogen.Semantic proximity Read ↗

A critical role of LFA-1 in the development of Th17 cells and induction of experimental autoimmune encephalomyelytis.Semantic proximity Read ↗

Cytosolic localization of Listeria monocytogenes triggers an early IFN-gamma response by CD8+ T cells that correlates with innate resistance to infection.Semantic proximity Read ↗

LSP1 modulates leukocyte populations in resting and inflamed peritoneum.Semantic proximity Read ↗

Susceptibility to Intracellular Infections: Contributions of TNF to Immune DefenseSemantic proximity Read ↗

Enhanced Susceptibility of Galectin-1 Deficient Mice to Experimental Colitis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.