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[A new method for 5, 10-methylenetetrahydrofolate reductase single nucleotide polymorphisms genotyping used to study susceptibility of hematological malignancy].

Zhongguo shi yan xue ye xue za zhi - 1 Dec 2006

Chen Bao-An, Jiang Ni, Ji Mei-Ju, Hou Peng, Lu Zu-Hong, Gao Chong, Ding Jia-Hua, Sun Yun-Yu, Wang Jun, Cheng Jian, Zhao Gang

Abstract excerpt

The aim of this study was to set up a new method for 5, 10-Methylenetetrahydrofolate reductase (MTHFR) single nucleotide polymorphisms (SNP) genotyping, and to investigate the hereditary susceptibility of hematological malignancy. Prepared an aimed gene microarray based on cDNA microarray theory, dual-color fluorescence hybridization was used to detect SNP loci, and DNA sequencing was performed to confirm the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17204166

Genes

MTHFR

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