Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A naturally occurring variant of porcine Mx1 associated with increased susceptibility to influenza virus in vitro.

Biochemical genetics - 1 Feb 2007

Nakajima Emiko, Morozumi Takeya, Tsukamoto Kenji, Watanabe Tomomasa, Plastow Graham, Mitsuhashi Tadayoshi

Abstract excerpt

Mx1 has been implicated in resistance to the influenza virus. We have now identified four alleles of the Mxl gene in domesticated breeds of pigs. Two of the alleles encode deletion variants (a 3-bp deletion in exon 13 and an 11-bp deletion in exon 14), which might be expected to interfere with Mx...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to GTP-Binding Proteins
Share to Influenza A Virus, H3N2 Subtype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interferons

Share to Myxovirus Resistance Proteins

Share to NIH 3T3 Cells

Share to Orthomyxoviridae Infections

Share to Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 17203407
DOI: 10.1007/s10528-006-9045-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17203407-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A naturally occurring variant of porcine Mx1 associated with increased susceptibility to influenza virus in vitro.PMID 17203407Read ↗

Polymorphisms in the promoter region of the porcine antiviral MX1 and MX2 genes.Semantic proximity Read ↗

Identification of a short interspersed repetitive element insertion polymorphism in the porcine MX1 promoter associated with resistance to porcine reproductive and respiratory syndrome virus infection.Semantic proximity Read ↗

A single nucleotide polymorphism of porcine MX2 gene provides antiviral activity against vesicular stomatitis virus.Semantic proximity Read ↗

GTPase activity of porcine Mx1 plays a dominant role in inhibiting the N-Nsp9 interaction and thus inhibiting PRRSV replication.Semantic proximity Read ↗

Differential anti-influenza activity among allelic variants at the Sus scrofa Mx1 locus.Semantic proximity Read ↗

Eurasian Avian-Like Swine Influenza A Viruses Escape Human MxA Restriction through Distinct Mutations in Their NucleoproteinSemantic proximity Read ↗

Genomic structure and diversity of the chicken Mx gene.Semantic proximity Read ↗

Protective role of interferon-induced Mx GTPases against influenza virusesSemantic proximity Read ↗

Interferons, Mx Genes, and Resistance to Influenza VirusSemantic proximity Read ↗

Mx1 Gene Protects Mice Against the Highly Lethal Human H5N1 Influenza VirusSemantic proximity Read ↗

Polymorphism distribution and structural conservation in RNA-sensing Toll-like receptors 3, 7, and 8 in pigs.Semantic proximity Read ↗

Influenza A Virus Strains Differ in Sensitivity to the Antiviral Action of Mx-GTPaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.