Article
In silico whole-genome screening for cancer-related single-nucleotide polymorphisms located in human mRNA untranslated regions.
BMC genomics - 3 Jan 2007
Aouacheria Abdel, Navratil Vincent, López-Pérez Ricardo, Gutiérrez Norma C, Churkin Alexander, Barash Danny, Mouchiroud Dominique, Gautier Christian
Abstract excerpt
BACKGROUND: A promising application of the huge amounts of genetic data currently available lies in developing a better understanding of complex diseases, such as cancer. Analysis of publicly available databases can help identify potential candidates for genes or mutations specifically related to the cancer phenotype. In spite of their huge potential to affect gene function, no systematic attention has been paid...
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