Article
Effect of photoreceptor degeneration on RNA splicing and expression of AMPA receptors.
Molecular vision - 13 Dec 2006
Namekata Kazuhiko, Okumura Akinori, Harada Chikako, Nakamura Kazuaki, Yoshida Hiroshi, Harada Takayuki
Abstract excerpt
PURPOSE: Glutamate is the most important neurotransmitter for excitatory synapses, and its ionotropic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor is widely expressed in the vertebrate retina. AMPA receptors are hetero-oligomers composed of subsets of four distinct subunits termed GluR1-4. This study was conducted to examine the developmental progression of the flip-to-flop alternative...
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