Article
ASF/SF2 and SC35 regulate the glutamate receptor subunit 2 alternative flip/flop splicing.
FEBS letters - 1 Aug 2005
Crovato Trine Elkjaer, Egebjerg Jan
Abstract excerpt
The properties of the glutamate receptor subunits 1-4 (GluR1-4) are influenced by the alternative splicing of two homologous and mutually exclusive exons flip and flop. The flip form is most abundant during early development, while the flop form is dominant in adults. From transfections with a GluR2 mini-gene we show that flip is the preferred splice form in all tested cell lines, but coexpression of the...
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