Article
beta2-Adrenergic receptor gene variants and risk for autism in the AGRE cohort.
Molecular psychiatry - 1 Mar 2007
Cheslack-Postava K, Fallin M D, Avramopoulos D, Connors S L, Zimmerman A W, Eberhart C G, Newschaffer C J
Abstract excerpt
The beta2-adrenergic receptor is part of the catecholamine system, and variants at two polymorphic sites in the gene coding for the receptor (ADRB2) confer increased activity. Overstimulation of this receptor may alter brain development, and has been linked to autism in non-identical twins. The objective of this study was to determine whether alleles in ADRB2 are associated with diagnosis of autism in the Autism...
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