Article
Free fetal DNA is not increased before 20 weeks in intrauterine growth restriction or pre-eclampsia.
Prenatal diagnosis - 1 Feb 2007
Crowley A, Martin C, Fitzpatrick P, Sheils O, O'Herlihy C, O'Leary J J, Byrne B M
Abstract excerpt
BACKGROUND: The aim of this study was to quantify maternal plasma fetal DNA and total DNA in early pregnancy in intrauterine growth restriction (IUGR) or pre-eclampsia (PET). METHODS: A nested case control study was carried out in a University Teaching Hospital. Plasma samples were obtained from 1993 women before 20 weeks of gestation. Pregnancies complicated by IUGR or PET were identified and compared to...
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