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Daryamides A−C, Weakly Cytotoxic Polyketides from a Marine-Derived Actinomycete of the Genus <i>Streptomyces</i> Strain CNQ-085

14 Nov 2006

Abstract excerpt

In the course of our continuing search for new antitumor-antibiotics from marine-derived actinomycete bacteria, four new cytotoxic compounds, designated as daryamides A (1), B (2), and C (3) and (2E,4E)-7-methylocta-2,4-dienoic acid amide (4), were isolated from the culture broth of a marine-derived Streptomyces strain CNQ-085. The structures of these new compounds were assigned by detailed interpretation of...

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PMID: 17190455
DOI: 10.1021/np0603828

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