Article
Empirical Bayes analysis of single nucleotide polymorphisms.
BMC bioinformatics - 6 Mar 2008
Schwender Holger, Ickstadt Katja
Abstract excerpt
BACKGROUND: An important goal of whole-genome studies concerned with single nucleotide polymorphisms (SNPs) is the identification of SNPs associated with a covariate of interest such as the case-control status or the type of cancer. Since these studies often comprise the genotypes of hundreds of thousands of SNPs, methods are required that can cope with the corresponding multiple testing problem. For the analysis...
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