Article
cAMP negatively regulates mRNA levels of actin and tropomyosin in rat cultured vascular smooth muscle cells.
Journal of biochemistry - 1 Jun 1991
Ohara O, Nakano T, Teraoka H, Arita H
Abstract excerpt
The isoform expression patterns of actin and actin-binding proteins have been reported to be good markers for phenotypic modulation of rat vascular smooth muscle cells. In order to elucidate the regulatory mechanism of actin and tropomyosin isoform expression on a molecular basis, we examined the...
Topics
- 1-Methyl-3-isobutylxanthine
- Actins
- Animals
- Base Sequence
- Bucladesine
- Cells, Cultured
- Colforsin
- Consensus Sequence
- Cyclic AMP
- Dactinomycin
- Immunoblotting
- Male
- Molecular Sequence Data
- Muscle, Smooth, Vascular
- Oligonucleotides
- Phenotype
- RNA, Messenger
- Rats