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Article

Effect of an epidermal growth factor receptor inhibitor in mouse models of lung cancer.

Molecular cancer research : MCR - 1 Dec 2006

Yan Ying, Lu Yan, Wang Min, Vikis Haris, Yao Ruisheng, Wang Yian, Lubet Ronald A, You Ming

Abstract excerpt

Gefitinib (Iressa, ZD1839) is a potent high-affinity competitive tyrosine kinase inhibitor aimed primarily at epidermal growth factor receptor (EGFR). Inhibitors in this class have recently been approved for clinical use in the treatment of advanced non-small cell lung cancer as monotherapy following failure of chemotherapy. We examined the efficacy of gefitinib on lung tumorigenesis in mouse models using both...

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Identifiers

PMID: 17189387
DOI: 10.1158/1541-7786.MCR-06-0086

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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