Article
Characterization of a human surfactant protein A1 (SP-A1) gene-specific antibody; SP-A1 content variation among individuals of varying age and pulmonary health.
American journal of physiology. Lung cellular and molecular physiology - 1 May 2007
Tagaram Hephzibah Rani S, Wang Guirong, Umstead Todd M, Mikerov Anatoly N, Thomas Neal J, Graff Gavin R, Hess Joseph C, Thomassen Mary Jane, Kavuru Mani S, Phelps David S, Floros Joanna
Abstract excerpt
The human surfactant protein A (SP-A) locus consists of two functional genes (SP-A1, SP-A2) with gene-specific products exhibiting qualitative and quantitative differences. The aim here was twofold: 1) generate SP-A1 gene-specific antibody, and 2) use this to assess gene-specific SP-A content in the bronchoalveolar lavage fluid (BALF). An SP-A1-specific polyclonal antibody (hSP-A1_Ab(68-88)_Col) was raised in...
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