Article
Mutation analysis of five candidate genes in familial breast cancer.
Breast cancer research and treatment - 1 Nov 2007
Marsh Anna, Healey Sue, Lewis Aaron, Spurdle Amanda B, Kedda Mary Anne, Khanna Kum Kum, Mann Graham J, Pupo Gulietta M, Lakhani Sunil R, Chenevix-Trench Georgia
Abstract excerpt
Most of the known breast cancer susceptibility genes (BRCA1, BRCA2, CHEK2 and ATM) are involved in the damage response pathway. Other members of this pathway are therefore good candidates for additional breast cancer susceptibility genes. ATR, along with ATM, plays a central role in DNA damage re...
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