Lack of association between macrophage migration inhibitory factor gene (-173 G/C) polymorphism and cutaneous vasculitis.

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Article

Lack of association between macrophage migration inhibitory factor gene (-173 G/C) polymorphism and cutaneous vasculitis.

Clinical and experimental rheumatology - 1 Jan 2000

Amoli M M, Martin J, Miranda-Filloy J A, Garcia-Porrua C, Ollier W E R, Gonzalez-Gay M A

Abstract excerpt

OBJECTIVE: To assess whether polymorphism of the macrophage migration inhibitory factor (MIF) gene at position -173 was implicated in the incidence of Henoch-Schönlein purpura (HSP) and cutaneous leukocytoclastic angiitis (CLA). A further objective was to determine if any relationship existed with severe systemic complications of HSP, in particular with severe renal involvement and permanent renal dysfunction....

Topics

Adolescent
Adult
Aged
Child
Child, Preschool
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
IgA Vasculitis
Kidney
Kidney Diseases
Macrophage Migration-Inhibitory Factors
Male
Middle Aged
Polymorphism, Genetic
Vasculitis, Leukocytoclastic, Cutaneous

Source

Open in PubMed

Identifiers

PMID: 17181929

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