Article
Genome-wide linkage in Utah autism pedigrees.
Molecular psychiatry - 1 Oct 2010
Allen-Brady K, Robison R, Cannon D, Varvil T, Villalobos M, Pingree C, Leppert M F, Miller J, McMahon W M, Coon H
Abstract excerpt
Genetic studies of autism over the past decade suggest a complex landscape of multiple genes. In the face of this heterogeneity, studies that include large extended pedigrees may offer valuable insights, as the relatively few susceptibility genes within single large families may be more easily discerned. This genome-wide screen of 70 families includes 20 large extended pedigrees of 6-9 generations, 6...
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