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Article

Estimation of population heterozygosity and library construction-induced mutation rate from expressed sequence tag collections.

Genetics - 1 May 2007

Long A D, Beldade P, Macdonald S J

Abstract excerpt

Unigene alignments obtained from cDNA libraries made using multiple individuals are not currently used to estimate population heterozygosity, as they are known to harbor mutations created during library construction. We describe an estimator of population heterozygosity that utilizes only SNPs unlikely to be library construction artifacts.

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Identifiers

PMID: 17179075
DOI: 10.1534/genetics.106.063610
PMCID: PMC1893025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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