Article
A parallel coiled-coil tetramer with offset helices.
Biochemistry - 26 Dec 2006
Liu Jie, Deng Yiqun, Zheng Qi, Cheng Chao-Sheng, Kallenbach Neville R, Lu Min
Abstract excerpt
Specific helix-helix interactions are fundamental in assembling the native state of proteins and in protein-protein interfaces. Coiled coils afford a unique model system for elucidating principles of molecular recognition between alpha helices. The coiled-coil fold is specified by a characteristic seven amino acid repeat containing hydrophobic residues at the first (a) and fourth (d) positions. Nonpolar side...
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