Article
Common variants of the neuropeptide expressing tachykinin genes and susceptibility to asthma: a case-control study.
Journal of neuroimmunology - 8 Oct 2010
Klassert Tilman E, Sánchez Juan J, Almeida Teresa A, Candenas Luz, Pinto Francisco, Acosta Orlando, Hernández Mariano
Abstract excerpt
Since tachykinins appear to be involved in the pathogenesis of allergic asthma, we investigated a possible association between 28 single nucleotide polymorphisms of the tachykinin genes TAC1, TAC3 and TAC4, and asthma susceptibility. A case-control study was conducted on 102 patients and 100 healthy subjects from the Canary Islands (Spain). A significant association with asthma was observed for two SNPs:...
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