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Article

Lipoprotein-associated phospholipase A2 A379V variant is associated with body composition changes in response to exercise training.

Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Jan 2007

Wootton Peter T E, Flavell David M, Montgomery Hugh E, World Mike, Humphries Steve E, Talmud Philippa J

Abstract excerpt

Lipoprotein-associated PLA2 (Lp-PLA2) hydrolyses the sn-2 position of glycerophospholipids, in particular platelet activating factor (PAF), generating significant amounts of Lyso-PAF which in turn, via a remodelling pathway, can generate arachidonic acid (AA) from alkyl-acyl-glycerophosphorylcholine. AA is a precursor for prostaglandin synthesis, which regulates adipogenesis through the peroxisome...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17174223
DOI: 10.1016/j.numecd.2005.11.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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