Article
A portrait of the geographic dissemination of the Clostridium difficile North American pulsed-field type 1 strain and the epidemiology of C. difficile-associated disease in Québec.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Jan 2007
Hubert Bruno, Loo Vivian G, Bourgault Anne-Marie, Poirier Louise, Dascal André, Fortin Elise, Dionne Marc, Lorange Manon
Abstract excerpt
BACKGROUND: An increase in the incidence and severity of Clostridium difficile-associated disease in Québec and the United States has been associated with a hypervirulent strain referred to as North American pulsed-field type 1 (NAP1)/027. METHODS: In 2005, a prospective study was conducted in 88 Québec hospitals, and 478 consecutive nosocomial isolates of C. difficile were obtained. The isolates were subjected...
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